GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| UCEC | cis | rs950169 | 1 | rs12902672 | chr15:84716986 | LOC388152 | chr15:84867600-84898920:- | -0.46 | -4.92 | 2.27E-6 | Schizophrenia |
| UCEC | cis | rs950169 | 1 | rs12903820 | chr15:84723820 | LOC388152 | chr15:84867600-84898920:- | -0.46 | -4.92 | 2.27E-6 | Schizophrenia |
| UCEC | cis | rs950169 | 1 | rs12915234 | chr15:84758301 | LOC388152 | chr15:84867600-84898920:- | -0.47 | -4.83 | 3.25E-6 | Schizophrenia |
| UCEC | cis | rs950169 | 1 | rs12916348 | chr15:84765527 | LOC388152 | chr15:84867600-84898920:- | -0.47 | -4.83 | 3.25E-6 | Schizophrenia |
| UCEC | cis | rs9894429 | 1 | rs12948099 | chr17:79600799 | TSPAN10 | chr17:79609349-79615778:+ | 0.62 | 7.56 | 3.56E-12 | Eye color traits |
| UCEC | cis | rs9815354 | 1 | rs13087719 | chr3:41951576 | ULK4 | chr3:41288091-42003660:- | -0.51 | -6.27 | 3.63E-9 | Diastolic blood pressure |
| UCEC | cis | rs13135092 | 1 | rs13135092 | chr4:103198082 | UBE2D3 | chr4:103715547-103790032:- | 0.71 | 4.41 | 1.92E-5 | HDL cholesterol |
| UCEC | cis | rs1577917 | 1 | rs13194429 | chr6:86646705 | SNHG5 | chr6:86386726-86388451:- | -0.46 | -5.4 | 2.49E-7 | Response to antipsychotic treatment |
| UCEC | cis | rs1577917 | 1 | rs13196930 | chr6:86652245 | SNHG5 | chr6:86386726-86388451:- | -0.53 | -5.93 | 1.94E-8 | Response to antipsychotic treatment |
| UCEC | cis | rs1577917 | 1 | rs13199006 | chr6:86608708 | SNHG5 | chr6:86386726-86388451:- | -0.46 | -5.96 | 1.65E-8 | Response to antipsychotic treatment |
| UCEC | cis | rs1577917 | 1 | rs13217384 | chr6:86720000 | SNHG5 | chr6:86386726-86388451:- | -0.45 | -5.56 | 1.16E-7 | Response to antipsychotic treatment |
| UCEC | cis | rs7017914 | 1 | rs13252719 | chr8:71734569 | XKR9 | chr8:71581600-71648176:+ | 0.76 | 10.35 | 2.43E-19 | Bone mineral density |
| UCEC | cis | rs7017914 | 1 | rs13253842 | chr8:71625503 | XKR9 | chr8:71581600-71648176:+ | 0.76 | 10.28 | 3.75E-19 | Bone mineral density |
| UCEC | cis | rs965469 | 1 | rs1331215 | chr20:3376565 | ITPA | chr20:3190056-3204504:+ | -0.41 | -4.47 | 1.52E-5 | IFN-related cytopenia |
| UCEC | cis | rs9815354 | 1 | rs13325965 | chr3:41914942 | ULK4 | chr3:41288091-42003660:- | 0.44 | 4.65 | 7.09E-6 | Diastolic blood pressure |